Melatonin is a hormone (N‑acetyl-5‑methoxytryptamine) produced especially at night in the pineal gland. Its secretion is stimulated by darkness and inhibited by light. Melatonin, an indole, is synthesized from tryptophan via serotonin. The suprachiasmatic nuclei (SCN) of the hypothalamus have melatonin receptors and melatonin may have a direct action on SCN to influence circadian (sleep) rhythms.
Adults: Spray 4-22 times daily under the tongue (4, 11, and 22 sprays provide approximately 1.5, 5, and 10 mg of melatonin, respectively) or as directed by your health-care practitioner. Sensitivity to melatonin is different from person to person. Take once a day, at or before bedtime.
Each spray contains:
|Melatonin (N‑acetyl-5‑methoxytryptamine)||440 mcg|